What is Emeset 8 used for?

Emeset 8 tablets 8mg are used to treat and prevent nausea and vomiting caused by certain cancer treatments including cancer chemotherapy and radiotherapy, which are used to kill cancer cells. Emeset 8 is also used to prevent post-operative nausea and vomiting. Emeset 8 helps to control and manage the onset of nausea and vomiting following cancer treatment and following surgery but it is not effective at preventing nausea and vomiting due to other causes like motion sickness, which are caused by a different mechanism.
How does Emeset 8 work?

Emeset 8 tablets 8mg contains ondansetron, a potent and highly selective 5HT3 receptor-antagonist that is used as an antiemetic to control the nausea and vomiting associated with cancer chemotherapy and radiotherapy, also to prevent post-operative nausea and vomiting. It is thought that chemotherapy, radiotherapy and surgery can cause the release of serotonin (5HT) from the cells of the small intestine, which stimulates 5HT3 receptors that are found on the vagal nerves in the intestines. Stimulation of these nerve endings by serotonin sends nerve messages to the vomiting centre in the brain (a complex area of neuronal networks) that induces the vomiting reflex. Ondansetron is thought to work by blocking the transmission of nerve messages from the intestines to the vomiting centre in the brain. There are also 5HT3 receptors in the chemoreceptor trigger zone (CTZ) of the area postrema in the brain, which is where the vomiting reflex originates, by sending nerve messages to the vomiting centre. It is thought that ondansetron in Emeset 8 also blocks the 5HT3 receptors in the CTZ and this also prevents activation of the vomiting centre in the brain. Ondansetron in Emeset 8 thereby blocks the 5HT3 receptors found in the peripheral nervous system in the intestine and the central nervous system in the brain. This dual effect of ondansetron in Emeset 8 prevents vomiting caused by chemotherapy and radiotherapy; also post-surgery vomiting and also helps relieve the feelings of nausea.